Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1260 |
[Pyr1]-Apelin-13
[pGlu1]-Apelin-13,人牛吡啶APELIN-13 |
Apelin receptor | GPCR/G Protein |
[Pyr1]-Apelin-13 ([pGlu1]-Apelin-13) 是一种高效的、内源性 apelin 受体选择性激动剂。 | |||
TP2001 |
MM 54
|
||
Potent apelin receptor antagonist (Ki = 82 nM; IC50 = 93 nM). Antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Recuces tumor expansion and lengthens survival time in a mouse xenograft model |